Ann Georgelas Cline, MS
The Huntsman Cancer Institute (HCI) Tissue Resource and Applications Core (TRAC) Shared Resource supports Cancer Center members by collecting, storing, tracking, processing, and distributing human tissue biospecimens. TRAC currently tracks more than 30,000 specimens through a Biospecimen Tracking (BST) Database, which links important clinical and pathological information with collected specimens. The vast majority of cancer patients (>90%) undergoing surgery at HCI consent to donate tissue and blood for research purposes.
The mission of the TRAC is to provide high-quality, clinically annotated specimens and superior service to the broad University of Utah (U of U) research community. Cancer specimens of all types are collected by TRAC under IRB #10924 Molecular Classifications of Cancer. This protocol was established to streamline the process of collecting, tracking, and utilizing cancer biospecimens for researchers at the U of U. Collection of fresh tissue for research is a TRAC priority. On average, TRAC procures approximately 20 percent of tissues as fresh frozen. In addition, clinical specimens, archived as formalin-fixed, paraffin-embedded tissue, are readily accessible for research from the Pathology Department on all consented patients. Samples collected by TRAC primarily come from within the U of U; however, protocols are in place for collection of specimens at other hospitals within the greater Salt Lake City area. TRAC's IRB protocol is linked to several clinical and research databases at the U of U, including the Data Warehouse, the Tumor Registry, and the Utah Population Database. Thus, the integrity and accuracy of clinical data associated with specimens collected by the Resource are ensured by established quality-control measures.
Tissue Resource and Applications Core Governance
Ann Georgelas Cline, MS
HCI Senior Director Oversight
David A. Jones, PhD
Faculty Advisory Committee Co-Chairs
Philip Bernard, MD
Mary Bronner, MD
Joshua Schiffman, MD
Faculty Advisory Committee Members
Melissa Cessna, MD (Intermountain Healthcare)
Michael Deininger, MD, PhD
Stephen Lessnick, MD, PhD
Sean Tavtigian, PhD
Alana Welm, PhD
If use of this resource results in a publication, please acknowledge the Cancer Center Support Grant by using the following text: "The project described was supported by Award Number P30CA042014 from the National Cancer Institute. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Cancer Institute or the National Institutes of Health."