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Experimental Therapeutics

Experimental Therapeutics Member Directory

ccsgexperimentalprogramThe Experimental Therapeutics (ET) program is a Cancer Center Support Grant (CCSG) program specifically organized to facilitate the development and validation of experimental therapeutic approaches for cancer applications. The ET program draws from resources within Huntsman Cancer Institute (HCI) and leverages the existing strengths of the University of Utah in genetics, pharmaceutics, and imaging. Program membership, scientific expertise and interests, and goals are specifically aligned with the vision of making individualized oncology a reality. ET program goals include the following:

  • Provide new approaches to individualized cancer diagnosis and therapy by developing new imaging techniques, diagnostics, and therapeutics, including image-guided and targeted drug delivery systems
  • Foster bidirectional translation of discoveries between the laboratory and the clinic by developing collaborations and scientific synergy among Cancer Center Program members
  • Better understand unmet clinical needs in cancer through collaboration and interaction with HCI Multidisciplinary Disease Groups
  • Advance theoretical and preclinical projects toward human applications in collaborative research projects
  • Develop and execute investigator-initiated clinical trials to establish new treatments for patients

The expertise of its members, from various departments from the colleges of Science, Pharmacy, Medicine, and Engineering, provides for truly cross-disciplinary research in cancer.

The ET program has been organized into three thematic areas based on the membership's scientific interests and expertise and the vision of the program and Cancer Center as a whole.

Imaging: use of molecular imaging and image-guided therapy to improve diagnosis, therapy, and clinical careidtgraphic1

Diagnostics: development of novel diagnostic strategies for cancer characterization to improve therapies and to provide prognostic information to improve clinical care

Therapeutics: development of novel drugs and drug delivery systems, involving preclinical development, pharmacology, and clinical trials, both sponsored and investigator-initiated

The three thematic areas of scientific interest and expertise in the ET program facilitate linking basic science to clinical oncology with the resulting outcome of a significant programmatic interest in investigator-initiated trials for imaging, diagnostics, and therapeutics. The program structure also facilitates the use of CCSG Shared Resources to improve the quality of cancer-related research and clinical trials performed by ET program members.

The Experimental Therapeutics Program currently receives approximately $9.1 million per year of direct research support from the National Institutes of Health, the National Science Foundation, and other funding agencies, with 36% coming from the National Cancer Institute. Cancer-focused articles published between 2003 and 2009 total 466, of which 15% are inter-programmatic and 17% are intra-programmatic publications.

 

Sunil Sharma, MD                John M. Hoffman, MD
Co-Leader                             Co-Leader

sharma s biohoffman j bio 

HCI, Room 3380                  HCI, Room 2121
801-587-5597                      801-587-4064

 

ET Membership Directory



A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

A

 

 

  • Agarwal, Neeraj

    Department: Medicine; Division of Oncology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-0255
    Research Interest: Prostate and kidney cancers

  • Akerley, Wallace

    Department: Medicine; Division of Oncology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-3453
    Research Interest: Experimental therapeutics, clinical trials in oncology, lung cancer and melanoma

  • Andtbacka, Robert

    Department: Surgery
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-4499
    Research Interest: New modalities for the detection of sentinel lymph nodes in patients with melanoma and breast cancer

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B

 

  • Bae, You Han

    Department: Pharmaceutics and Pharmaceutical Chemistry
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-1518
    Research Interest: Anticancer drug carrier design targeting MDR

  • Barnette, Phillip

    Department: Pediatrics; Division of Pediatric Hematology/Oncology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-5543
    Research Interest: Oncology trials in pediatric patients

  • Barrows, Louis

    Department: Pharmacology and Toxicology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-4547
    Research Interest: Colon cancer, retinoic acid, DNA methylation, cancer therapeutics

  • Bearss, David

    Department: Oncological Sciences
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-4561
    Research Interest: Use of computational approaches to modeling protein-small molecule interactions to discover potential drug candidates and algorithm development for developing models to predict ADME characteristics of small molecules for use in drug discovery

  • Bernard, Philip

    Department: Pathology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-5353
    Research Interest: Molecular diagnostics of solid and soft tumors

  • Bild, Andrea

    Department: Pharmacology and Toxicology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-6353
    Research Interest: Signal transduction in tumor initiation and metastasis

  • Bronner, Mary

    Department: Pathology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-4326
    Research Interest: Gastrointestinal cancers arising in chronic inflammatory disease, such as inflammatory bowel disease, gastritis, Barnetts, pancreatitis, and hepatitis

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C

  • Cohen, Adam

Department: Medicine; Division of Oncology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 587-4725
Research Interest: New therapies and personalization of therapy in breast cancer and primary brain tumors

  • Colman, Howard

Department: Neurosurgery
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-0270
Research Interest: Identification and validation of novel biomarkers of prognosis and treatment response in primary brain tumors and the isolation, characterization, and use of brain tumor stem cells for drug discovery and identification of novel therapeutic targets

 

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D

 

 

  • DiBella, Edward

    Department: Radiology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-5543
    Research Interest: Mathematical models to quantify physiological parameters of cancer from MRI

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E

 

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F

  • Firpo, Matt

    Department: Surgery
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-9049
    Research Interest: Pancreatic cancer

  • Furgeson, Darin

    Department: Pharmaceutics and Pharmaceutical Chemistry 
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-7271
    Research Interest: Cleaning dirty tumor margins with thermo-targeted chemotherapy and microwave ablation; Recominant siRNA delivery vehicles to treat neuro-disease across the blood brain barrier

 

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G

 

  • Gaffney, David

    Department: Radiation Oncology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-2396
    Research Interest: Radiotherapy for gynecology, breast, and lymphoma

  • Garrido-Laguna, Ignacio
  • Department: Medicine; Division of Oncology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: 801-585-1435
    Research Interest: Pancreatic cancer, drugs targeting stroma, EMT

  • Ghandehari, Hamid

    Department: Pharmaceutics and Pharmaceutical Chemistry
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-1566
    Research Interest: Design of new polymers for gene therapy of head and neck cancer

  • Grissom, Charles

    Department: Biochemistry
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-4153
    Research Interest: Cancer drug development, tumor imaging, lymph node imaging

  • Grossmann, Kenneth 

    Department: Medicine; Division of Oncology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-4735
    Research Interest: Resistance mechanisms in targeted therapy and epigenetic change especially in melanoma 

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H

 

  • Hoffman, John

    Department: Radiology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-4064
    Research Interest: Molecular imaging, particularly positron emission tomography (PET) imaging in cancer patients

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I

 

  • Ireland, Chris

    Department: Medicinal Chemistry
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-8305
    Research Interest: Cancer genetics, marine natural products

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J

 

  • Janát-Amsbury, Margit

    Department: Obstetrics/Gynecology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 213-2248
    Research Interest: The development of novel, mainly nanotechnology-based systems for clinical cancer therapy

  • Jensen, Randy

    Department: Neurosurgery
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-6908
    Research Interest: Brain tumor angiogenesis and hypxoxia

 

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K

 

  • Kadrmas, Dan

    Department: Radiology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-5937
    Research Interest: Biomaterials and drug delivery, positron emission tomography (PET) imaging

  • Khong, Hung

    Department: Internal Medicine
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 213-4260
    Research Interest: Immuntherapy of cancer; third generation biochemotherapy; epigenetic modulation in the treatment of cancer; novel combination of chemotherapy/targeted therapy - CV
    CCSG Program: Imaging, Diagnostics, and Therapeutics (IDT)

  • Kim, Sung Wan

    Department: Pharmaceutics and Pharmaceutical Chemistry
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-6801
    Research Interest: Medical polymers and drug delivery, angiogenesis targeting

  • Kopecek, Jindrich

    Department: Pharmaceutics and Pharmaceutical Chemistry
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-7211
    Research Interest: Biomaterials and drug delivery

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L

 

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M

 

  • McGreevy, James

    Department: Surgery
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-4488
    Research Interest: Identification of novel tumor markers

 

  • Morrell, Glen

    Department: Radiology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-7553
    Research Interest: Breast MRI and MRI characterization of breast cancer

  • Morton, Kathryn

    Department: Radiology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-9068
    Research Interest: Molecular imaging, PET scanning in cancer

  • Mulvihill, Sean

    Department: Surgery
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-7304
    Research Interest: Biology of pancreatic cancer

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N

O

 

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P

 

  • Parker, Dennis

    Department: Radiology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-8654
    Research Interest: MR angiography, MRI scanner design, MRI guided thermal ablation of tumors

  • Porter, Marc

    Department: Pathology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-8654
    Research Interest: Innovations in nanotechnology for the creation of ultrasensitive and real-time assays for the detection of cancer markers including PSA and pancreatic cancer

  • Prchal, Josef

    Department: Hematology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-3229
    Research Interest: Germ line and somatic mutations leading to disease hematopoiesis, identifying the molecular basis of these disorders

  • Pulsipher, Michael

    Department: Pediatrics; Division of Pediatric Hematology/Oncology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 588-2680
    Research Interest: Reduced intensity allogeneic transplantation, transplantation of pediatric ALL, hematopoietic stem cell donor safety

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Q

 

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R

 

  • Randall, R. Lor

    Department: Orthopaedics
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-7601
    Research Interest: Genetics of sarcoma

  • Rapoport, Natalya

    Department: Bioengineering
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 231-2480
    Research Interest: Combined ultrasonography and ultrasound-mediated chemotherapy of drug-sensitive and multidrug resistant tumors

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S

 

  • Scaife, Courtney

    Department: Surgery
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-6911
    Research Interest: Pancreas cancer modeling and mechanisms of metastases

  • Shami, Paul

    Department: Medicine; Division of Hematology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-0255
    Research Interest: Nitric oxide and hematopoietic cell biology, acute leukemia and myelodysplatic syndromes

  • Sharma, Sunil

    Department: Medicine; Division of Oncology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 587-5597
    Research Interest: Gastrointestinal cancers (colon, pancreatic, esophageal, rectal, liver), mesothelioma, and rare tumors (carcinoid, neuroendocrine tumors, and carcinomas of unknown primarys)

  • Shea, Jill E.

    Department: Surgery
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-0593
    Research Interest: Gain a better understanding of the importance of tumor-stroma interactions in the progression of pancreas cancer, and through this knowledge improve patient care by assisting in the development of new imaging and treatments for this devastating cancer.
    CCSG Program: Imaging, Diagnostics, and Therapeutics (IDT)

  • Shrieve, Dennis

    Department: Radiation Oncology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-8793
    Research Interest: Assessment of the intrinsic radiosensitivity of human tumors, mechanisms of intrinsic cellular resistance to radiation and chemotherapy and combined chemotherapy/radiotherapy, clinical trials in brain tumors

  • Sklow, Brad

    Department: Surgery
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 581-7124
    Research Interest: Molecular genetics of colon cancer

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T

 

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U

 

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V

  •  Verma, Anupam

    Department: Pediatric Hematology/Oncology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 662-4700
    Research Interest: Translational research for development of novel target drugs for childhood cancers. Early phase clinical trials in children with cancer - CV
    CCSG Program: Imaging, Diagnostics, and Therapeutics (IDT)

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W

 

  • Ward, John

    Department: Medicine; Division of Oncology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-0255
    Research Interest: Breast cancer management

  • Werner, Theresa

    Department: Medicine; Division of Oncology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 585-0255
    Research Interest: High risk breast/ovarian cancer

 

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X

 

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Z

 

  • Zangari, Maurizio

    Department: Medicine; Division of Hematology
    E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
    Phone: (801) 213-2281
    Research Interest: New treatments for patients with multiple myeloma, tandem autologous transplantation for treatment of multiple myeloma, personalized treatment strategies for the treatment of myeloma

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