CRR Membership Directory
CRR Winter 2012 Newsletter
CRR 2012 Summer Newsletter
CRR 2011 Winter Newsletter
CRR 2011 Summer Newsletter
CRR 2010 Winter Newsletter
CRR 2010 Summer Newsletter
The Cell Response and Regulation (CRR) program conducts basic and translational research on the fundamental cellular mechanisms that are deregulated in cancer cells. This research provides new insight into cancer pathways and potential biomarkers.
The CRR program brings together scientists with shared research interests in two main thematic areas:
- Cell turnover in cancer, including control of cell division and cell death and their dysregulation in cancer, as well as stem cell biology and how it informs us about tumor-initiating cells
- Tumor microenvironment, particularly cellular processes that initiate, promote, and maintain cancer metastasis, as well as the role of inflammation and oxidative stress in the tumor microenvironment
Several members use animal models to characterize cell and tumor behavior in organisms. The diverse expertise in techniques and model systems offers great opportunity for synergistic projects and stimulating scientific exchange. This extends across Cancer Center Programs and is further promoted by the interface with disease focus groups.
The CRR program draws its members from many academic units on campus and provides a forum for interdepartmental communication among individuals who share a common interest in understanding the cellular basis of cancer.
The Cell Response and Regulation program currently receives approximately $6.7 million per year of direct research support from the National Institutes of Health, the American Cancer Society, and other funding agencies, with 13% coming from the National Cancer Institute. Cancer-focused articles published between 2003 and 2009 total 202, of which 31% are inter-programmatic and 11% are intra-programmatic publications.
Douglas Grossman, MD, PhD | Katherine S. Ullman, PhD | |
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| HCI, Room 5243 (801) 581-4682 (801) 585-7477 FAX | HCI, Room 5345 (801) 585-7123 (801) 587-8344 FAX |
CRR Membership Directory
A
- Angus-Hill, Melinda
Department: Medicine; Division of Gastroenterology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 213-4240
Research Interest: Gene function during colon development, adult tissue homeostasis, and tumorigenesis through the use of mouse models
B
- Baron, Riccardo
Department: Medicinal Chemistry
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-7117
Research Interest: Develop and apply computational chemistry to investigate the coupling among biomolecular structure, (thermo)dynamics, and function at diverse spatiotemporal scales.
- Beckerle, Mary
Department: Biology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 581-4485
Research Interest: Cell adhesion, cell migration, Ewing's sarcoma
C
- Cassidy, Pamela
Department: Medicinal Chemistry
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 581-6268
Research Interest: The role of selenium and selenoproteins in cancer, especially melanoma; oxidative stress and cancer - Christian, Jan
Department: Neurobiology and Anatomy/Medicine; Division of Hematology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 581-5397
Research Interest: Cellular mechanisms that regulate Wnts and Bone morphogenetic proteins - Cohen, Michael B.
Department: Pathology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 213-4341
Research Interest: Understanding signaling pathways in prostate cancer as a prelude to the development of more, better therapeutic strategies and approaches.
CCSG Program: Cell Response and Regulation (CCSG)
D
- Deininger, Michael
Department: Medicine; Division of Hematoloy
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 581-6363
Research Interest: Hematological malignancies and solid tumors, high-dose therapy and autologous stem cell transplantation
E
F
- Factor, Rachel
Department: Pathology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 587-4763
Research Interest: How breast cancer pathology relates to tumor behavior
- Frost, Adam
Department: Biochemistry
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 581-8899
Research Interest: Basic mechanisms of cellular physiology and to understand how malignancy changes these mechanisms
- Fults, Daniel
Department: Neurosurgery
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 581-6908
Research Interest: Defective signaling in medulloblastoma
G
- Grossman, Douglas
Department: Dermatology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 581-4682
Research Interest: Apoptotic mechanisms underlying skin cancer development, with a focus on the apoptosis and cell cycle regulator, Survivin
H
- Holmen, Sheri
Department: Surgery
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: 801-213-4237
Research Interest: Identifying and validating novel molecular targets for cancer therapy
I
J
- Jette, Cicely
Department: Oncological Sciences
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 587-5568
Research Interest: Using zebrafish model system to identify new therapeutic targets to restore normal cell death pathways to cancer cells
K
- Kadrmas, Julie
Department: Oncological Sciences
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 581-4793
Research Interest: Cell adhesion and migration in cancer
L
- Li, Dean
Department: Medicine; Division of Cardiology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-5505
Research Interest: Signaling in angiogenesis; targeting angiogenesis in cancer
- Lim, Carol
Department: Pharmaceutics and Pharmaceutical Chemistry
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 587-9711
Research Interest: Targeting apoptotic mechanisms in cancer cells
M
- Moos, Philip
Department: Pharmacology and Toxicology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-5952
Research Interest: Redox dysregulation in cancer, selenoprotein function in cancer, cancer prevention
- Murtaugh, L. Charles
Department: Human Genetics
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 581-5958
Research Interest: Pancreatic development and cancer
N
O
- O'Hare, Thomas
Department: Medicine; Division of Hematology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-0256
Research Interest: Target discovery and inhibitor development for chronic and acute leukemias; mechanism-based targeting of leukemic cells, including leukemia stem cells; design, validation, and coordination of function-first profiling for new therapeutic targets in leukemia - Oliver, Trudy
Department: Oncoligical Sciences
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 213-4221
Research Interest: Therapeutic response and resistance using mouse models of cancer; Regulation of the Mdm2/p53 tumor suppressor pathway
P
- Planelles, Vicente
Department: Pathology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 581-8655
Research Interest: Regulation of cell cycle and apoptosis signaling
- Prchal, Josef
Department: Hematology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-3229
Research Interest: Germ line and somatic mutations leading to myeloproliferative disorders
Q
R
- Rosenblatt, Jody
Department: Oncological Sciences
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 587-4073
Research Interest: Mechanisms and regulation of cell death and division, novel mechanisms for initiating tumor cell metastasis
S
- Sigman, Matthew
Department: Chemistry
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-0774
Research Interest: Synthesis and biological evaluation of novel small molecule platforms; mechanism of action studies of the resultant hits
- Spangrude, Gerald
Department: Medicine; Division of Hematology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-5544
Research Interest: Stem cell biology
- Stafforini, Diana
Department: Medicine; Division of Cardiology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-340
Research Interest: Role of inflammation in cancer - Stanfield, Gillian
Department: Human Genetics
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-9944
Research Interest: Cell polarity, cell migration, and the role of proteases in cancer
- Sundquist, Wesley
Department: Biochemistry
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-5402
Research Interest: Membrane trafficking and cytokinesis
T
- Topham, Matthew
Department: Medicine; Division of Pulmonary Medicine
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-3404
Research Interest: Lipid signaling in cancer
U
- Ullman, Katharine
Department: Oncological Sciences
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Phone: (801) 585-7123
Research Interest: Cell division, biomarkers and tumor suppressors in breast cancer
V
- VanBrocklin, Matthew
Department: Surgery
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: 801-213-4236
Research Interest: Using pre-clinical models of cancer to identify and validate potential molecular components vital for tumor initiation
W
- Wang, Li
Department: Medicine; Division of Gastroenterology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 587-4616
Research Interest: Role of orphan nuclear receptor SHP (small heterodimer partner) in development of hepatocellular carcinoma and colon cancer - Welm, Alana
Department: Oncological Sciences
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 587-4622
Research Interest: Tumor inflammation and cancer, particularly breast cancer
- Welm, Bryan
Department: Surgery
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 587-4633
Research Interest: Breast cancer stem cells, cancer drug screening - Williams, Matthew
Department: Pathology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 587-4477
Research Interest: My lab seeks to understand the cellular and molecular signals that regulate the differentiation and cell fate decisions of sctivated T cells in vivo - CV
CCSG Program: Cell Response and Regulation (CRR)
X
Y
- Yost, H. Joseph
Department: Neurobiology and Anatomy
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-6110
Research Interest: Extracellular matrix, tumor suppressor screens in zebrafish
Z
- Zhan, Fenghuang
Department: Medicine; Division of Hematology
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 213-3718
Research Interest: Define and target genes or their signaling pathways related to drug resistance and stem cell in myeloma
- Zimmerman, Guy
Department: Medicine; Division of Pulmonary Medicine
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Phone: (801) 585-0727
Research Interest: Cell adhesion and inflammation; thrombosis in cancer
